James D. Watson

"Should you be allowed to make an anti-Semitic remark? Yes, because some anti-Semitism is justified. Just like some anti-Irish feeling is justified. If you cant be criticized, thats very dangerous. The whole Larry Summers thing, to say that men are a bit strange and their strangest quality is their ability to understand mathematics -- youre not supposed to even think it."

"There is only one science, physics: everything else is social work."

"To have success in science, you need some luck. But to succeed in science, you need a lot more than luck. And its not enough to be smart — lots of people are very bright and get nowhere in life. In my view, you have to combine intelligence with a willingness not to follow conventions when they block your path forward."

"Moving forward will not be for the faint of heart. But if the next century witnesses failure, let it be because our science is not yet up to the job, not because we dont have the courage to make less random the sometimes most unfair courses of human evolution."

"I just can’t sit while people are saying nonsense in a meeting without saying it’s nonsense."

"Never do anything that bores you. My experience in science is that someone is always telling to do something that leaves you flat. Bad idea. Im not good enough to do something I dislike. In fact, I find it hard enough to do something that I like. … Constantly exposing your ideas to informed criticism is very important, and I would venture to say that one reason both of our chief competitors failed to reach the Double Helix before us was that each was effectively very isolated."

"To make a huge success, a scientist must be prepared to get into deep trouble. Sometime or another, someone will tell you that you are not ready to do something. … If you are going to make a big jump in science, you will very likely be unqualified to succeed by definition. The truth, however, wont save you from criticism. Your very willingness to take on a very big goal will offend some people who will think that you are too big for your britches and crazy to boot."

"Science Ph.D. students have effectively become serfs. And who would become a serf when you can work for Goldman Sachs and get paid $300,000 a year to become a serf? Why drive a Chevy when you can drive a BMW — and now youre condemned to driving a car from Malaysia or something. Life should be fun."

"No one may have the guts to say this, but if we could make better human beings by knowing how to add genes, why shouldnt we?"

"I turned against the left wing because they dont like genetics, because genetics implies that sometimes in life we fail because we have bad genes. They want all failure in life to be due to the evil system."

"The brain is the last and grandest biological frontier, the most complex thing we have yet discovered in our universe. It contains hundreds of billions of cells interlinked through trillions of connections. The brain boggles the mind."

"Whenever you interview fat people, you feel bad, because you know youre not going to hire them."